BONE-MARROW AFTER AUTOLOGOUS BLOOD STEM-CELL TRANSPLANTATION AND TOTAL-BODY IRRADIATION - MAGNETIC-RESONANCE AND CHEMICAL-SHIFT IMAGING

被引：12

作者：

KAUCZOR, HU

BRIX, G

DIETL, B

JAROSCH, K

KNOPP, MV

VANKAICK, G

机构：

[1] Department of Radiology, German Cancer Research Center, 69120 Heidelberg

[2] Department of Radiology, University of Mainz, 55101 Mainz

[3] Department of Radiotherapy, University of Heidelberg, 69120 Heidelberg

[4] Department of Radiotherapy, University of Regensburg, 93053 Regensburg

来源：

MAGNETIC RESONANCE IMAGING | 1993年 / 11卷 / 07期

关键词：

BLOOD STEM CELL TRANSPLANTATION; TOTAL BODY IRRADIATION; MAGNETIC RESONANCE IMAGING; CHEMICAL SHIFT IMAGING;

D O I：

10.1016/0730-725X(93)90216-Z

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Magnetic resonance studies of the lumbar, pelvic, and femoral bone marrow were performed in 10 patients after autologous blood stem cell transplantation, including total body irradiation and myeloablative chemotherapy. The posttreatment interval varied between 2 and 6 yr. The appearance on T1-weighted images and the quantitative data obtained from chemical shift imaging (relative fat signal) were compared to 10 age-matched healthy volunteers. The classification of the T1-weighted images yielded no significant differences between the two groups. Chemical shift imaging by determination of the relative fat signal was able to detect a significant fatty replacement of the patients' lumbar (p < .002) and pelvic marrow (p < .01), showing the clinically inapparent decreased cellularity of the bone marrow. This difference did not change within the interval of 2-6 yr after transplantation.

引用

页码：965 / 975

页数：11

共 41 条

[1]

Daffner, Lupertin, Dash, Deeb, Sefczek, Schapiro, MRI in the detection of malignant infiltration of bone marrow, AJR, 146, pp. 353-358, (1986)

[2]

Vogler, Murphy, Bone marrow imaging, Radiology, 168, pp. 679-693, (1988)

[3]

Smith, Williams, Edwards, Davies, Quantitative magnetic resonance imaging in autologous bone marrow transplantation for Hodgkin's disease, Br. J. Cancer, 60, pp. 961-965, (1989)

[4]

Stevens, Moore, Amylon, Repopulation of marrow after transplantation: MR imaging with pathologic correlation, Radiology, 175, pp. 213-218, (1990)

[5]

Hanna, Fletcher, Fairclough, Jenkins, Le, Magnetic resonance imaging of disseminated bone marrow disease in patients treated for malignancy, Skeletal Radiol., 20, pp. 79-84, (1991)

[6]

Ricci, Cova, Kang, Yang, Rahmouni, Scott, Zerhouni, Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton. MR imaging study, Radiology, 177, pp. 83-88, (1990)

[7]

Dewes, Ruhlmann, Loos, Vogel, Krahe, Hotze, Harder, MR tomography in lymphatic and leukaemic bone infiltrations, Fortschr. Röntgenstr., 147, pp. 654-661, (1987)

[8]

Guckel, Semmler, Dohner, Knauf, Gorich, Ho, van Kaick, Kernspintomographische Darstellung von Knochenmarkinfiltrationen bei malignen Lymphomen, RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 150, pp. 26-31, (1989)

[9]

Kaplan, Asleson, Klassen, Duggan, Bone marrow pattern in aplastic anemia: Observations with 1.5-T MR imaging, Radiology, 164, pp. 441-444, (1987)

[10]

Dietl, Kauczor, Brix, Semmler, van Kaick, Wannenmacher, Late bone marrow changes in Hodgkin's disease patients: A characterization with proton chemical shift imaging, Eur. Radiol., 2, pp. 204-208, (1992)

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