Heterotopic pregnancies (simultaneous ectopic and intrauterine pregnancies) can occur spontaneously or associated with assisted reproductive technology. It is infrequent in Mexico. We present a case of heterotopic pregnancy in a 32 year old woman submitted to surgery due to rupture of the ectopic pregnancy located in the right fallopian tube. The evolution was satisfactory for the woman, but the newborn died shortly after delivery because of meconium aspiration. We review the literature on this disease.