FUNCTIONAL CLONING OF A DICTYOSTELIUM-DISCOIDEUM CDNA-ENCODING GMP SYNTHETASE

被引：0
|
作者：
CAMPAGNE, MMV
FRANKE, J
KESSIN, RH
机构：
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 1991年 / 266卷 / 25期
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中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A functional cloning procedure has been used to recover a cDNA coding for the GMP synthetase of Dictyostelium discoideum. The enzyme is encoded by a single gene, which is actively transcribed during growth, but not during development. The open reading frame encodes a protein of 718 amino acids with a predicted molecular mass of 79.6 kDa. The Dictyostelium enzyme has extensive homology with the GMP synthetase of Escherichia coli and regional homology to other glutamine amidotransferases.
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页码：16448 / 16452
页数：5
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