STEREOSELECTIVE SYNTHESIS OF (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYL-PENTANOIC ACID, AN AMINO-ACID CONSTITUENT OF BLEOMYCIN, BY ALDOL CONDENSATION

被引：38

作者：

NARITA, M

OTSUKA, M

KOBAYASHI, S

OHNO, M

UMEZAWA, Y

MORISHIMA, H

SAITO, SI

TAKITA, T

UMEZAWA, H

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

[2] INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

来源：

TETRAHEDRON LETTERS | 1982年 / 23卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)86879-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：525 / 528

页数：4

共 18 条

[11]

REID W, 1959, LIEBIGS ANN CHEM, V622, P37

[12]

SAITO S, 1982, TETRAHEDRON LETT, V23, P525

[13] CHEMISTRY OF BLEOMYCIN .19. REVISED STRUCTURES OF BLEOMYCIN AND PHLEOMYCIN [J].

TAKITA, T ;

MURAOKA, Y ;

NAKATANI, T ;

FUJII, A ;

UMEZAWA, Y ;

NAGANAWA, H ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1978, 31 (08) :801-804

[14] TOTAL SYNTHESIS OF BLEOMYCIN-A2 [J].

TAKITA, T ;

UMEZAWA, Y ;

SAITO, SI ;

MORISHIMA, H ;

NAGANAWA, H ;

UMEZAWA, H ;

TSUCHIYA, T ;

MIYAKE, T ;

KAGEYAMA, S ;

UMEZAWA, S ;

MURAOKA, Y ;

SUZUKI, M ;

OTSUKA, M ;

NARITA, M ;

KOBAYASHI, S ;

OHNO, M .

TETRAHEDRON LETTERS, 1982, 23 (05) :521-524

[15] TOTAL SYNTHESIS OF DEGLYCO-BLEOMYCIN-A2 [J].

TAKITA, T ;

UMEZAWA, Y ;

SAITO, S ;

MORISHIMA, H ;

UMEZAWA, H ;

MURAOKA, Y ;

SUZUKI, M ;

OTSUKA, M ;

KOBAYASHI, S ;

OHNO, M .

TETRAHEDRON LETTERS, 1981, 22 (07) :671-674

[16] TOTAL SYNTHESIS OF THE DISACCHARIDE OF BLEOMYCIN, 2-O-(ALPHA-D-MANNOPYRANOSYL)-L-GULOPYRANOSE [J].

TSUCHIYA, T ;

MIYAKE, T ;

KAGEYAMA, S ;

UMEZAWA, S .

TETRAHEDRON LETTERS, 1981, 22 (15) :1413-1416

[17] CHEMISTRY OF BLEOMYCIN .14. BIOGENETIC-LIKE SYNTHESIS OF (2S, 3S, 4R)-4-AMINO-3-HYDROXY-2-METHYL-N-VALERIC ACID, AN AMINE COMPONENT OF BLEOMYCIN [J].

YOSHIOKA, T ;

HARA, T ;

TAKITA, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1974, 27 (05) :356-357

[18]

1981, 101ST ANN M PHARM SO

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