AMINO ACIDS AND PEPTIDES .15. PREPARATION OF (ARG-GLY-ASP)-(AMINO-POLY(ETHYLENE GLYCOL)) HYBRIDS AND THEIR INHIBITORY EFFECT ON EXPERIMENTAL METASTASIS

被引：0

作者：

KAWASAKI, K ^{[1
]}

NAMIKAWA, M ^{[1
]}

YAMASHIRO, Y ^{[1
]}

HAMA, T ^{[1
]}

MAYUMI, T ^{[1
]}

机构：

[1] OSAKA UNIV, FAC PHARMACEUT SCI, SUITA, OSAKA 565, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1991年 / 39卷 / 12期

关键词：

RGD; POLY(ETHYLENE GLYCOL); PEPTIDE-POLY(ETHYLENE GLYCOL)HYBRID; DRUG-CARRIER; ANTITUMOR; FIBRONECTIN;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Hybrids of a fibronectin-related tripeptide (Arg-Gly-Asp) and amino-poly(ethylene glycol) were prepared and their inhibitory effect on experimental metastasis in mice was examined. The hybrids exhibited a potent inhibitory effect on the metastasis of B16 melanoma BL6.

引用

页码：3373 / 3375

页数：3

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