Cytokeratin positivity in secondary angiosarcoma of breast: A diagnostic pitfall

被引：0

作者：

Gupta, Prakriti ^{[1
]}

Rao, Seema ^{[2
]}

Bhalla, Sunita ^{[2
]}

机构：

[1] Sir Ganga Ram Hosp, Dept Pathol, New Delhi, India

[2] Sir Ganga Ram Hosp, Dept Histopathol, New Delhi, India

来源：

CLINICAL CANCER INVESTIGATION JOURNAL | 2018年 / 7卷 / 03期

关键词：

Angiosarcoma; breast; carcinoma; cytokeratin positivity; secondary;

D O I：

10.4103/ccij.ccij_16_18

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Reappearing breast lump in a known case of breast carcinoma often turns out to be a recurrence of the carcinoma. However, in patients receiving radiotherapy for the disease, possibility of secondary angiosarcoma should also be suspected. Secondary angiosarcoma can pose a challenge in pathological diagnosis especially in small trucut biopsies. Aberrant expression of epithelial marker can also add to the difficulty. In this article, we report a case wherein similar difficulties were faced during the diagnosis.

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页码：119 / 121

页数：3

相关论文

共 9 条

[1] The risk of angiosarcoma following primary breast cancer [J].

Cozen, W ;

Bernstein, L ;

Wang, F ;

Press, MF ;

Mack, TM .

BRITISH JOURNAL OF CANCER, 1999, 81 (03) :532-536

[2] Primary and secondary angiosarcomas of the breast: a single institution experience [J].

Fraga-Guedes, Conceicao ;

Gobbi, Helenice ;

Mastropasqua, Mauro Giuseppe ;

Botteri, Edoardo ;

Luini, Alberto ;

Viale, Giuseppe .

BREAST CANCER RESEARCH AND TREATMENT, 2012, 132 (03) :1081-1088

[3]

OHSAWA M, 1995, CANCER, V75, P2867, DOI 10.1002/1097-0142(19950615)75:12<2867::AID-CNCR2820751212>3.0.CO

[4]

2-8

[5] Primary and Secondary Angiosarcoma of the Breast: The Mayo Clinic Experience [J].

Scow, Jeffrey S. ;

Reynolds, Carol A. ;

Degnim, Amy C. ;

Petersen, Ivy A. ;

Jakub, James W. ;

Boughey, Judy C. .

JOURNAL OF SURGICAL ONCOLOGY, 2010, 101 (05) :401-407

[6] Postirradiation epithelioid angiosarcoma of the breast: A case report with immunohistochemical and electron microscopic study [J].

Seo, IS ;

Min, KW .

ULTRASTRUCTURAL PATHOLOGY, 2003, 27 (03) :197-203

[7]

Singh, 1996, Breast Cancer, V3, P125, DOI 10.1007/BF02966973

[8] Mammary angiosarcomas: Imaging findings in 24 patients [J].

Yang, Wei Tse ;

Hennessy, Bryan T. J. ;

Dryden, Mark J. ;

Valero, Vicente ;

Hunt, Kelly K. ;

Krishnamurthy, Savitri .

RADIOLOGY, 2007, 242 (03) :725-734

[9] Sarcoma as a second malignancy after treatment for breast cancer [J].

Yap, J ;

Chuba, PJ ;

Thomas, R ;

Aref, A ;

Lucas, D ;

Severson, RK ;

Hamre, M .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 52 (05) :1231-1237