EFFECTIVENESS OF LIPIODOL IN TRANSCATHETER ARTERIAL EMBOLIZATION OF HEPATOCELLULAR-CARCINOMA

被引:18
作者
NAKAO, N
UCHIDA, H
KAMINO, K
NISHIMURA, Y
OHISHI, H
TAKAYASU, Y
NAKAMURA, H
KURODA, C
FUJITA, M
YOSHIOKA, H
ISHIDA, O
机构
[1] NARA MED UNIV,DEPT RADIOL,KASHIHARA,NARA 634,JAPAN
[2] OSAKA UNIV,SCH MED,DEPT RADIOL,OSAKA,JAPAN
[3] CTR ADULT DIS,DEPT RADIOL,OSAKA 537,JAPAN
[4] KINKI UNIV,SCH MED,DEPT RADIOL,OSAKA,OSAKA 577,JAPAN
关键词
HEPATOCELLULAR CARCINOMA; TRANSCATHETER ARTERIAL EMBOLIZATION; LIPIODOL (IODIZED OIL);
D O I
10.1007/BF00687110
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The effectiveness of Lipiodol (iodized oil) in transcatheter arterial embolization (TAE) of hepatocellular carcinoma (HCC) was retrospectively evaluated using statistical analysis. A total of 343 HCC patients who underwent TAE at 5 institutions between 1984 and 1989 were divided into 2 groups: the GS-TAE group underwent TAE with Gelfoam sponge alone, whereas the LP-TAE group was given Lipiodol (LP) immediately before GS-TAE. The statistical T value calculated for the LP-TAE group showed that the administration of LP, the tumor size, intrahepatic metastasis, portal vein infiltration, and serum total bilirubin and alpha-fetoprotein levels significantly (P <0.01) affected the patients' survival. Both the cumulative survival determined using the Kaplan-Meier model and the cumulative hazard calculated using Cox's proportional hazard model differed significantly (P <0.01) between the GS-TAE group and the LP-TAE group (log-rank test). These results confirmed the effectiveness of LP used in combination with Gelfoam sponge for TAE of HCC.
引用
收藏
页码:S72 / S76
页数:5
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