SALIVARY TESTOSTERONE LEVELS AND MAJOR DEPRESSIVE-ILLNESS IN MEN

被引：40

作者：

DAVIES, RH

HARRIS, B

THOMAS, DR

COOK, N

READ, G

RIADFAHMY, D

机构：

[1] UNIV WALES COLL MED,DEPT PSYCHOL MED,CARDIFF CF4 4XN,S GLAM,WALES

[2] UNIV HOSP WALES,TENOVUS INST,STEROID ASSAY LAB,CARDIFF,WALES

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1992年 / 161卷

关键词：

D O I：

10.1192/bjp.161.5.629

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Studies of testosterone levels in patients with major depressive illness have produced varying results, plasma levels usually being reported. Saliva levels reflect 'free' plasma testosterone, and a pilot study of 11 men with major depression with melancholia, who underwent a standard dexamethasone suppression test, is described. There were no significant differences in testosterone levels compared with an age-matched control group. In the patient group, predexamethasone levels correlated significantly and negatively with depression ratings on the 21-item Hamilton and the Montgomery and Asberg depression scales, and also with state anxiety measured on the Spielberger scale.

引用

页码：629 / 632

页数：4

共 27 条

[1]

American Psychiatric Association, 1980, DIAGN STAT MAN MENT, V3rd

[2] DIET-HORMONE INTERACTIONS - PROTEIN CARBOHYDRATE RATIO ALTERS RECIPROCALLY THE PLASMA-LEVELS OF TESTOSTERONE AND CORTISOL AND THEIR RESPECTIVE BINDING GLOBULINS IN MAN [J].