HERQULINE, A NEW ALKALOID PRODUCED BY PENICILLIUM-HERQUEI FERMENTATION, ISOLATION AND PROPERTIES

被引：46

作者：

OMURA, S ^{[1
]}

HIRANO, A ^{[1
]}

IWAI, Y ^{[1
]}

MASUMA, R ^{[1
]}

机构：

[1] KITASATO INST,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 08期

关键词：

D O I：

10.7164/antibiotics.32.786

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new alkaloid named herquline has been isolated from culture broth of Penicillium herquei Fg-372 by solvent extraction and silica gel chromatography. The molecular formula of herquline has been determined as C19H26N2O2 on the basis of elemental analysis and its high resolution mass spectrometry. The compound does not possess antimicrobial activities, but weakly inhibits blood platelet aggregation induced by adenosine diphosphate. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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页码：786 / 790

页数：5

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