ELECTRON CAPTURE RESPONSE FOLLOWING GAS LIQUID CHROMATOGRAPHY OF VARIOUS HALOGENATED DERIVATIVES OF 17BETA-OESTRADIOL AND OESTRONE

被引：26

作者：

EXLEY, D

DUTTON, A

机构：

[1] M.R.C. Neuroendocrinology Unit, Department of Human Anatomy, University of Oxford

来源：

STEROIDS | 1969年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0039-128X(69)80048-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various halogenated derivatives of oestradiol and oestrone have been prepared and their response to electron capture following gas liquid chromatography and their stability to thin layer chromatography determined. Some of the iodomethyldimethylsilyl ethers have been found to be more sensitive than their corresponding heptafluorobutyric esters. It has been found that electron capture response increases according to I>Cl>F. Points regarding the relationship of structure of derivative to electron capturing capability are discussed. © 1968 Holden-Day, Inc.

引用

页码：575 / &

共 15 条

[1]

ATTAL J, 1967, J ANAL BIOCHEM, V20, P394

[2] IODINE AS A LOCATION REAGENT IN THIN-LAYER CHROMATOGRAPHY IODINATION OF PHENOLS [J].

BROWN, W ;

TURNER, AB .

JOURNAL OF CHROMATOGRAPHY, 1967, 26 (02) :518-&

[3]

CORKER CS, 1969, J ENDOCRINOL, V43, pR30

[4]

EABORN C, IN PRESS

[5] PROPERTIES OF STEROIDAL 3 ENOL HEPTAFLUOROBUTYRATES [J].

EXLEY, D ;

CHAMBERLAIN, J .

STEROIDS, 1967, 10 (05) :509-+

[6]

EXLEY D, 1967, COMPTES RENDUS TABLE

[7]

EXLEY D, 1967, ACTA ENDOCRIN S, V119, P100

[8]

GEE W, 1964, J CHEM SOC, P2845

[9] THIOLESTERS OF PERFLUOROCARBOXYLIC ACIDS [J].

HAUPTSCHEIN, M ;

STOKES, CS ;

NODIFF, EA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (16) :4005-4010

[10]

KAESZ HD, 1957, J CHEM SOC, P1433

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