INTRAOPERATIVE RADIOTHERAPY FOR GLIOMAS

被引：23
|
作者：
FUJIWARA, T [1 ]
HONMA, Y [1 ]
OGAWA, T [1 ]
IRIE, K [1 ]
KUYAMA, H [1 ]
NAGAO, S [1 ]
TAKASHIMA, H [1 ]
HOSOKAWA, A [1 ]
OHKAWA, M [1 ]
TANABE, M [1 ]
机构：
[1] KAGAWA MED SCH,DEPT RADIOL,MIKI,KAGAWA 76107,JAPAN
来源：
JOURNAL OF NEURO-ONCOLOGY | 1995年 / 23卷 / 01期
关键词：
GLIOMA; INTRAOPERATIVE RADIOTHERAPY;
D O I：
10.1007/BF01058463
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Intraoperative radiotherapy (IORT) was performed in 20 of 36 patients with glioma; 11 glioblastomas, 7 malignant astrocytomas, 2 benign astrocytomas. Twenty or 25 Gy of irradiation was delivered in a single fraction intraoperatively, followed by external beam irradiation. The electron beam energy was selected so that the 80% isodose line fell at 20 or 3 cm below the residual tumor surface. Median survival time of IORT group was 14 months and that of the control group was 10 months. Difference of survival curve was significant. There were 6 incidences of complication caused by IORT; 1 radionecrosis, 1 convulsion, 1 abscess, and 3 severe brain edemas. IORT is suited for the treatment of malignant gliomas.
引用
收藏
页码：81 / 86
页数：6
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