The Effects of Slow Withdrawal of Antiepileptic Drugs on Seizure Clusters and Status Epilepticus: Results of Long-Term Video-EEG Monitoring

被引：0

作者：

Barcin, Ebru Nur ^{[1
]}

Gusnal, Gnseli Gul ^{[2
]}

Aktekin, Berrin ^{[3
]}

机构：

[1] Akdeniz Univ, Tip Fak, Norol Anabilim Dali, Antalya, Turkey

[2] Antalya Ataturk Devlet Hastanesi, Norol Klin, Antalya, Turkey

[3] Yeditepe Univ, Tip Fak, Norol Anabilim Dali, Istanbul, Turkey

来源：

EPILEPSI | 2013年 / 19卷 / 02期

关键词：

Antiepileptic drugs; drug resistant epilepsy; seizure clustering; status epilepticus; video-EEG monitoring;

D O I：

10.5505/epilepsi.2013.44154

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: In this retrospective study, frequency of seizure clustering and occurrence of status epilepticus were investigated in patients with drug resistant focal epilepsy who were admitted in long term video-EEG monitoring unit (VEM) for presurgical evaluation. Methods: The VEM records of 49 patients (26 female, 23 male; mean age 26.35 +/- 10.2 years) between April 2004-April 2008 were reviewed. Results: Although there was no status epilepticus occured, seizure clustering was observed in 21 (% 42.9) patients during VEM. Conclusion: Seizure clustering was common during presurgical VEM. The risk of seizure clustering might be reduced with a slow antiepileptic drugs tapering protocol and to avoid changing the presently used benzodiazepine dosage.

引用

页码：53 / 57

页数：5

共 45 条

[41] Impact of antiepileptic drugs for seizure prophylaxis on short and long-term functional outcomes in patients with acute intracerebral hemorrhage: A meta-analysis and systematic review [J].

Spoelhof, Brian ;

Sanchez-Bautista, Julian ;

Zorrilla-Vaca, Andres ;

Kaplan, Peter W. ;

Farrokh, Salia ;

Mirski, Marek ;

Freund, Brin ;

Rivera-Lara, Lucia .

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2019, 69 :140-146

[42] Long-term effects of status epilepticus during infancy in male rats: Sexual behavior and brain response upon exposure to sexually receptive females [J].

Chena-Becerra, Florencia ;

Alfonso Coria-Avila, Genaro ;

Beltran-Parrazal, Luis ;

Manzo, Jorge ;

Leonor Lopez-Meraz, Maria .

EPILEPSY & BEHAVIOR, 2020, 102

[43] Safety and efficacy of rapid withdrawal of antiseizure medications during long-term video-electroencephalogram monitoring in children with drug-resistant epilepsy: A retrospective study [J].

Wang, Shuang ;

Wang, Wen ;

Yu, Guojing ;

Wan, Lin ;

Fan, Yuying ;

Wang, Hongjie ;

Liu, Tong ;

Ji, Taoyun ;

Liu, Qingzhu ;

Cai, Lixin ;

Liu, Xiaoyan .

EPILEPSIA OPEN, 2023, 8 (02) :313-319

[44] Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis [J].

Han, Yujuan ;

Yang, Jiaxin ;

Zhong, Rui ;

Guo, Xin ;

Cai, Mengtan ;

Lin, Weihong .

NEUROLOGICAL SCIENCES, 2022, 43 (09) :5217-5227

[45] Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy [J].

Wheless, James W. ;

Miller, Ian ;

Hogan, R. Edward ;

Dlugos, Dennis ;

Biton, Victor ;

Cascino, Gregory D. ;

Sperling, Michael R. ;

Liow, Kore ;

Vazquez, Blanca ;

Segal, Eric B. ;

Tarquinio, Daniel ;

Mauney, Weldon ;

Desai, Jay ;

Rabinowicz, Adrian L. ;

Carrazana, Enrique .

EPILEPSIA, 2021, 62 (10) :2485-2495

← 1 2 3 4 5 →