Role of 25- Hydroxyvitamin D-3 in Patients with Atopic Dermatitis

被引：0

作者：

Abd-Elal, Essam B. ^{[1
]}

Abdo, Hamed M. A. ^{[1
]}

Abd-Alhameed, Mahmoud F. ^{[2
]}

Ahmed, Hanaa H. ^{[3
]}

Hassaan, Mohammed ^{[2
]}

机构：

[1] Al Azhar Univ, Dermatol Dept, Fac Med, Cairo, Egypt

[2] Natl Res Ctr, Dermatol Dept, Giza, Egypt

[3] Natl Res Ctr, Hormones Dept, Giza, Egypt

来源：

BIOSCIENCE RESEARCH | 2018年 / 15卷 / 04期

关键词：

Vitamin D; atopic dermatitis; deficiency; relationship;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The deficiency of vitamin D may be linked to atopic dermatitis (AD). The aim of this study was to estimate the serum level of 25-hydroxyvitamin D-3 in AD patients and its relation to the disease severity. The study was conducted on 100 participants distributed into 2 main groups: fifty patients suffering from AD and fifty healthy volunteers. The concentration of serum 25-hydroxyvitamin D3 was measured using ELISA technique. Correlation tests were done using Pearson correlation coefficient and ANOVA test was done for statistical evaluation of difference in means between groups. The results of this study showed decreased serum level of 25-hydroxyvitamin D-3 in AD patients versus controls. An inverse relationship between serum level of 25-hydroxyvitamin D-3 and AD severity was found. This relation was more pronounced in children than in adults. These data advocated the importance of further studies to assess the potential of vitamin D use as a novel therapy for atopic dermatitis.

引用

页码：2944 / 2949

页数：6

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