14-BETA-HYDROXY-10-DEACETYLBACCATIN-III, A NEW TAXANE FROM HIMALAYAN YEW (TAXUS-WALLICHIANA ZUCC)

被引：67

作者：

APPENDINO, G

GARIBOLDI, P

GABETTA, B

PACE, R

BOMBARDELLI, E

VITERBO, D

机构：

[1] INDENA SPA,I-20141 MILAN,ITALY

[2] DIPARTIMENTO CHIM INORGAN CHIM FIS & CHIM MAT,I-10125 TURIN,ITALY

[3] DIPARTIMENTO SCI CHIM,I-63032 CAMERINO,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 21期

关键词：

D O I：

10.1039/p19920002925

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The needles of T. wallichiana Zucc. gave a new taxane, whose structure was established as 14beta-hydroxy-10-deacetylbaccatin III on the basis of chemical reactions, spectroscopic data and X-ray analysis.

引用

页码：2925 / 2929

页数：5

共 18 条

[1] SCIENTISTS MOBILIZE TO INCREASE SUPPLY OF ANTICANCER DRUG TAXOL [J].

BORMAN, S .

CHEMICAL & ENGINEERING NEWS, 1991, 69 (35) :11-18

[2] H-1-NMR AND C-13-NMR ASSIGNMENTS FOR TAXOL, 7-EPI-TAXOL, AND CEPHALOMANNINE [J].

CHMURNY, GN ;

HILTON, BD ;

BROBST, S ;

LOOK, SA ;

WITHERUP, KM ;

BEUTLER, JA .

JOURNAL OF NATURAL PRODUCTS, 1992, 55 (04) :414-423

[3] A HIGHLY EFFICIENT, PRACTICAL APPROACH TO NATURAL TAXOL [J].

DENIS, JN ;

GREENE, AE ;

GUENARD, D ;

GUERITTEVOEGELEIN, F ;

MANGATAL, L ;

POTIER, P .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (17) :5917-5919

[4]

ETTOUATI L, 1989, B SOC CHIM FR, P687

[5]

ETTOUATI L, 1988, B SOC CHIM FR, P749

[6] STRUCTURE OF A SYNTHETIC TAXOL PRECURSOR - N-TERT-BUTOXYCARBONYL-10-DEACETYL-N-DEBENZOYLTAXOL [J].

GUERITTEVOEGELEIN, F ;

GUENARD, D ;

MANGATAL, L ;

POTIER, P ;

GUILHEM, J ;

CESARIO, M ;

PASCARD, C .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1990, 46 :781-784

[7] RELATIONSHIPS BETWEEN THE STRUCTURE OF TAXOL ANALOGS AND THEIR ANTIMITOTIC ACTIVITY [J].

GUERITTEVOEGELEIN, F ;

GUENARD, D ;

LAVELLE, F ;

LEGOFF, MT ;

MANGATAL, L ;

POTIER, P .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (03) :992-998

[8] STRUCTURE OF TAIWANXAN [J].

HO, TI ;

LIN, YC ;

LEE, GH ;

PENG, SM ;

YEH, MK ;

CHEN, FC .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1987, 43 :1380-1382

[9] SEPARATION OF CROSS-RELAXATION AND J-CROSS-PEAKS IN 2D ROTATING-FRAME NMR-SPECTROSCOPY [J].

KESSLER, H ;

GRIESINGER, C ;

KERSSEBAUM, R ;

WAGNER, K ;

ERNST, RR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (02) :607-609

[10] THE CHEMISTRY OF TAXOL, A CLINICALLY USEFUL ANTICANCER AGENT [J].

KINGSTON, DGI ;

SAMARANAYAKE, G ;

IVEY, CA .

JOURNAL OF NATURAL PRODUCTS, 1990, 53 (01) :1-12

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