INVITRO MODEL FOR STRETCH-INDUCED HYPERTROPHY OF SKELETAL-MUSCLE

被引：229

作者：

VANDENBURGH, H

KAUFMAN, S

机构：

[1] Laboratory of Neurochemistry, National Institute of Mental Health, Bethesda

来源：

SCIENCE | 1979年 / 203卷 / 4377期

关键词：

D O I：

10.1126/science.569901

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mechanical stretch of embryonic chicken skeletal myotubes developed in vitro leads to many of the biochemical changes seen in skeletal muscle hypertrophy. These include increased amino acid accumulation, increased incorporation of amino acids into general cellular proteins and myosin heavy chains, and increased accumulation of total protein and myosin heavy chains. This model system should aid in understanding how the growth rate of skeletal muscle is regulated by its activity. Copyright © 1979.

引用

页码：265 / 268

页数：4

共 35 条

[1] ANTIGENIC SPECIFICITY OF RED AND WHITE MUSCLE MYOSIN [J].