CHONDROCYTE BEHAVIOR IN FIBRIN GLUE IN-VITRO

被引：145

作者：

HOMMINGA, GN ^{[1
]}

BUMA, P ^{[1
]}

KOOT, HWJ ^{[1
]}

VANDERKRAAN, PM ^{[1
]}

VANDENBERG, WB ^{[1
]}

机构：

[1] UNIV HOSP NIJMEGEN,RHEUMATOL LAB,6500 HB NIJMEGEN,NETHERLANDS

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1993年 / 64卷 / 04期

关键词：

D O I：

10.3109/17453679308993663

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

To test fibrin glue as a vehicle in chondrocyte transplantation, chondrocytes, isolated from articular cartilage of young rabbits, were mixed with Tissucol(R), a highly concentrated fibrin glue, and cultured for 7 days. Histology, autoradiography (35-S) and electron microscopy were used to study chondrocyte behavior and phenotypic expression. Chondrocytes multiplied, retained their morphology, and produced matrix in fibrin glue as long as the cells were surrounded by the glue. Glue disintegration started after 3 days and was accelerated by higher cell concentrations.

引用

页码：441 / 445

页数：5

共 18 条

[1] ISOLATED EPIPHYSEAL CHONDROCYTE ALLOGRAFTS INTO JOINT SURFACES - EXPERIMENTAL-STUDY IN RABBITS [J].

BENTLEY, G ;

SMITH, AU ;

MUKERJHEE, R .

ANNALS OF THE RHEUMATIC DISEASES, 1978, 37 (05) :449-458

[2]

BUSCHMANN MD, 1991, COMBINED M ORTHOP RE

[3] CLONAL STABILITY AND PHENOTYPIC EXPRESSION OF CHICK CARTILAGE CELLS IN VITRO [J].

COON, HG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (01) :66-&

[4]

ELVES MW, 1974, J BONE JOINT SURG BR, VB 56, P178

[5] BIOCHEMICAL-STUDIES ON REPAIR CARTILAGE RESURFACING EXPERIMENTAL DEFECTS IN THE RABBIT KNEE [J].

FURUKAWA, T ;

EYRE, DR ;

KOIDE, S ;

GLIMCHER, MJ .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1980, 62 (01) :79-89

[6] NOTES ON ESTIMATION OF NUMERICAL DENSITY OF ARBITRARY PROFILES - EDGE EFFECT [J].

GUNDERSEN, HJG .

JOURNAL OF MICROSCOPY-OXFORD, 1977, 111 (NOV) :219-223

[7] SIGNIFICANCE OF INTERCELLULAR MATRIX IN SURVIVAL OF CARTILAGE ALLOGRAFTS [J].

HEYNER, S .

TRANSPLANTATION, 1969, 8 (05) :666-&

[8] REPAIR OF ARTICULAR DEFECTS BY PERICHONDRIAL GRAFT - EXPERIMENTS IN THE RABBIT [J].

HOMMINGA, GN ;

VANDERLINDEN, TJ ;

TERWINDTROUWENHORST, EAW ;

DRUKKER, J .

ACTA ORTHOPAEDICA SCANDINAVICA, 1989, 60 (03) :326-329

[9]

ITAY S, 1987, CLIN ORTHOP RELAT R, V220, P284

[10] FIXATION OF OSTEOCHONDRAL FRACTURES - FIBRIN SEALANT TESTED IN DOGS [J].

KELLER, J ;

ANDREASSEN, TT ;

JOYCE, F ;

KNUDSEN, VE ;

JORGENSEN, PH ;

LUCHT, U .

ACTA ORTHOPAEDICA SCANDINAVICA, 1985, 56 (04) :323-326

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