CIRCULATING INTERFERON-ALPHA IN PATIENTS WITH KYASANUR FOREST DISEASE

被引：0

作者：

SATHE, PS

DANDAWATE, CN

SHARADAMMA, K

GHOSH, SN

机构：

来源：

INDIAN JOURNAL OF MEDICAL RESEARCH SECTION A-INFECTIOUS DISEASES | 1991年 / 93卷

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D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Endogenous interferon (IFN) levels were monitored in acute (51) and convalescent phase (19) sera collected from patients suffering from Kyasanur forest disease (KFD). Levels of circulating IFN in the acute samples (GM 216.3 +/- 8.7) collected between 4 to 7 post onset day (POD) were significantly higher (P < 0.001) than the convalescent samples (GM 13.19 +/- 1.6) collected between 30th to 90th POD. Interferonemia was concomitant with the viraemic phase. Neutralization studies indicated that the endogenous (circulating) IFN was antigenically similar to acid stable form of IFN-alpha.

引用

页码：199 / 201

页数：3

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