SYNTHESIS OF NON-GLOBIN PROTEINS IN RABBIT-ERYTHROID CELLS - SYNTHESIS OF A LIPOXYGENASE IN RETICULOCYTES

被引：29

作者：

THIELE, BJ ^{[1
]}

BELKNER, J ^{[1
]}

ANDREE, H ^{[1
]}

RAPOPORT, TA ^{[1
]}

RAPOPORT, SM ^{[1
]}

机构：

[1] ACAD SCI GDR,ZENT INST MOLEK BIOL,DEPT BIOREGULAT,DDR-1115 BERLIN,GER DEM REP

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 96卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1979.tb13070.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Peripheral rabbit reticulocytes synthesize at least 30 non‐globin proteins. One of them is identified as a characteristic lipoxygenase on the basis of its molecular weight, its immunological properties and its behaviour on an ion‐exchange column. The enzyme is not produced in bone marrow cells. The synthesis of the lipoxygenase in peripheral blood cells commences on the 3rd day of a bleeding anaemia, increases up to the 5th day and stays constant thereafter at least up to the 14th day. It is concluded that the appearence of the lipoxygenase, which plays a key role in the degradation of mitochondria in the course of maturation of reticulocytes to erythrocytes, is regulated at the translational level. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：563 / 569

页数：7

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