ENZYME IMMOBILIZATION ON HEPARIN

被引：10

作者：

TORCHILIN, VP

ILINA, EV

STRELTSOVA, ZA

SMIRNOV, VN

CHAZOV, EI

机构：

[1] National Research Center of Cardiology, AMS USSR

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1978年 / 12卷 / 05期

关键词：

D O I：

10.1002/jbm.820120502

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We describe the preparation and some of the properties of heparin‐bound α‐chymotrypsin that were obtained via activation of heparin with water‐soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low‐molecular‐weight and macromolecular substrates. The heparin‐bound enzymes could have a wide range of medical applications. Copyright © 1978 John Wiley & Sons, Inc.

引用

页码：585 / 590

页数：6

共 12 条

[1]

AVRAMEAS S, 1967, J BIOL CHEM, V242, P1651

[2] CROSS-LINKING OF PROTEINS WITH GLUTARALDEHYDE AND ITS USE FOR PREPARATION OF IMMUNOADSORBENTS [J].