FET PET in Neuro-oncology and in Evaluation of Treatment Response

被引：3

作者：

Dunet, Vincent ^{[1
,2
]}

Prior, John O. ^{[1
]}

机构：

[1] Univ Lausanne Hosp, Dept Nucl Med, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[2] Univ Lausanne Hosp, Dept Radiol, CH-1011 Lausanne, Switzerland

来源：

PET CLINICS | 2013年 / 8卷 / 02期

关键词：

PET; F-18-fluoroethyltyrosine; FET; Amino acid PET; Brain tumor; Glioma;

D O I：

10.1016/j.cpet.2012.09.005

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Morphologic magnetic resonance imaging is the mainstay in the diagnosis and follow-up of primary brain tumor. However, it has limited ability to differentiate tumor from edema, necrosis, or fibrosis. PET with F-18-fluoro-ethyl-tyrosine (FET) is a promising and complementary diagnostic and prognostic tool to probe tumor biology in vivo. This article presents the tracer biology and uptake mechanism, the imaging protocol and quantitative image analysis, common pitfalls and variants, and the main indications for FET PET. Finally, a summary on what the referring physician needs to know about FET PET is presented.

引用

页码：147 / +

页数：17

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