SEASONAL DIFFERENCES AND EFFECT OF INSULIN ON PYRUVATE UPTAKE OXIDATION AND SYNTHESIS TO GLYCOGEN BY FROG SKELETAL MUSCLE

被引:22
|
作者
GOURLEY, DRH
SUH, TK
BRUNTON, LL
机构
[1] Department of Pharmacology, University of Virginia School of Medicine, Charlottesville
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1969年 / 29卷 / 02期
关键词
C[!sup]14[!/sup]O[!sub]2[!/sub; frog; glycogen; glycogenesis from pyruvate; insulin; muscle; oxygen consumption; pyruvate oxidation; pyruvate uptake; seasonal differences;
D O I
10.1016/0010-406X(69)91603-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. 1. In frog sartorius muscle, insulin stimulated the uptake of pyruvate, the synthesis of pyruvate to glycogen, and in summer, but not in winter, the oxidation of pyruvate. 2. 2. Insulin shifted the utilization of pyruvate away from pathways not studied in this investigation. In summer muscles, the major shift was toward oxidation, while in winter muscles, the major shift was toward glycogen synthesis. © 1969.
引用
收藏
页码:509 / +
页数:1
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