SELECTIVE ALTERATION OF SUBSTRATE-SPECIFICITY BY REPLACEMENT OF ASPARTIC ACID-189 WITH LYSINE IN THE BINDING POCKET OF TRYPSIN

被引:144
作者
GRAF, L
CRAIK, CS
PATTHY, A
ROCZNIAK, S
FLETTERICK, RJ
RUTTER, WJ
机构
[1] UNIV CALIF SAN FRANCISCO,HORMONE RES INST,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143
关键词
D O I
10.1021/bi00383a031
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:2616 / 2623
页数:8
相关论文
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