DESIGN, SYNTHESIS, AND EVALUATION OF DNA MINOR-GROOVE BINDING-AGENTS

被引:30
|
作者
BOGER, DL
机构
[1] The Scripps Research Institute, Department of Chemistry, La Jolla, California
关键词
D O I
10.1351/pac199365061123
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The design, synthesis, and evaluation of DNA minor groove binding agents related to (+)-CC-1065 and (+)-duocarmycin A are detailed in continuing efforts to define the structural origin of the sequence-selective DNA alkylation reaction.
引用
收藏
页码:1123 / 1132
页数:10
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