LONG-TERM HYPOTHERMIC STORAGE OF THE CARDIAC EXPLANT - COMPARISON OF 4 SOLUTIONS

被引:0
|
作者
WANG, TC
BATTY, PR
HICKS, GL
DEWEESE, JA
机构
来源
JOURNAL OF CARDIOVASCULAR SURGERY | 1991年 / 32卷 / 01期
关键词
COLD STORAGE; CARDIAC PRESERVATION; HEMODYNAMIC PERFORMANCE; ADENINE NUCLEOTIDES;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study compared the capabilities of 4 storage solutions in protecting the cardiac explant. Isolated rat heart was flushed with and stored in one of the storage solutions at 0-degrees-C for 7 hours. The recovery of function was assessed using the working heart perfusion. Cardiac output returned to 34 +/- 6, 59 +/- 3, 76 +/- 5, and 75 +/- 8% (mean +/- SE) of the control level in hearts stored in Euro-Collins, St. Thomas' Hospital cardioplegic, a modified University of Wisconsin (MUW) solutions, and a solution developed by us (CP-8), respectively. Therefore, MUW and CP-8 were superior to the other two solutions. During post-storage reperfusion, the coronary flow correlated directly with the aortic flow (r = 0.98), suggesting that preservation of coronary perfusion may be crucial to the recovery of function. There was also a good correlation between myocardial ATP levels and the cardiac output (r = 0.81). Thus, measurements towards the enhancement of ATP preservation and regeneration may be beneficial to the stored cardiac explant.
引用
收藏
页码:21 / 25
页数:5
相关论文
共 50 条
  • [21] LONG-TERM SOLUTIONS
    IVEY, SK
    SOUTH DAKOTA FARM & HOME RESEARCH, 1981, 32 (01): : 17 - 19
  • [22] HARVESTING HEARTS FOR LONG-TERM PRESERVATION - DETRIMENTAL EFFECTS OF INITIAL HYPOTHERMIC INFUSION OF CARDIOPLEGIC SOLUTIONS
    TAKAHASHI, A
    HEARSE, DJ
    BRAIMBRIDGE, MV
    CHAMBERS, DJ
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1990, 100 (03): : 371 - 378
  • [23] Microperfusion method for long-term heart hypothermic preservation
    Ferrera, R
    Michel, P
    Hadour, G
    Chiari, P
    Ovize, M
    Rodriguez, C
    EUROPEAN HEART JOURNAL, 2000, 21 : 87 - 87
  • [24] LONG-TERM STUDY AFTER HYPOTHERMIC KIDNEY PERFUSION
    EISENBERGER, F
    CHAUSSY, C
    HOFSTETTER, A
    MARX, FJ
    AKTUELLE UROLOGIE, 1977, 8 (05) : 239 - 242
  • [25] The effect of freezing and long-term storage on the stability of cardiac troponin T
    Basit, Majid
    Bakshi, Nasir
    Hashem, Mustafa
    Allebban, Zuhair
    Lawson, Noel
    Rosman, Howard S.
    Maciejko, James J.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007, 128 (01) : 164 - 167
  • [26] Rejuvenation capacity of RBC in additive solutions over long-term storage
    Meyer, E.
    Dumont, D.
    Baker, S.
    Dumont, Larry J.
    TRANSFUSION, 2008, 48 (02) : 163A - 163A
  • [27] STABILIZATION OF COPPER(I) CHLORIDE SOLUTIONS UNDER LONG-TERM STORAGE
    BORODINA, AV
    SEMENOV, VN
    KHIMICHESKAYA PROMYSHLENNOST, 1986, (01): : 62 - 62
  • [28] Long-term storage [Langzeitarchivierung]
    Borghoff U.M.
    Rödig P.
    Scheffczyk J.
    Schmitz L.
    Informatik Spektrum, 2005, 28 (6) : 489 - 492
  • [29] Super Long-Term Storage
    Hornyak, Timothy
    SCIENTIFIC AMERICAN, 2013, 308 (01) : 21 - 21
  • [30] Long-term storage of plutonium
    Wood, WT
    NUCLEAR MATERIALS SAFETY MANAGEMENT, 1998, 20 : 69 - 70