CLATHRIN LIGHT-CHAINS - ARRAYS OF PROTEIN MOTIFS THAT REGULATE COATED-VESICLE DYNAMICS

被引：84
作者：
BRODSKY, FM
HILL, BL
ACTON, SL
NATHKE, I
WONG, DH
PONNAMBALAM, S
PARHAM, P
机构：
[1] UNIV CALIF SAN FRANCISCO,SCH PHARM,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143
[2] STANFORD UNIV,DEPT CELL BIOL,STANFORD,CA 94305
[3] STANFORD UNIV,DEPT MICROBIOL & IMMUNOL,STANFORD,CA 94305
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 06期
关键词：
D O I：
10.1016/0968-0004(91)90087-C
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.
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页码：208 / 213
页数：6
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