SULFHYDRYL-GROUPS AND THE DIFFERENTIATION OF MURINE ERYTHROLEUKEMIA-CELLS

被引：7

作者：

MARESCA, B ^{[1
]}

JAFFE, BM ^{[1
]}

SANTORO, MG ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT SURG,ST LOUIS,MO 63130

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 03期

关键词：

D O I：

10.1016/0006-291X(79)92000-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The importance of cysteine and sulfhydryl groups has been demonstrated in relation to the differentiation and respiration of Friend erythroleukemia cells (FLC). The respiratory rate of undifferentiated FLC was higher basally (5.06 ± 0.16 vs. 3.10 ± 0.09 nmoles 02/min/106 cells) and was further 70% stimulated by addition of cysteine, whereas DMSO-induced differentiated cells were insensitive. A sulfhydryl blocking agent (PCMS) was capable of maintaining the differentiated state of FLC cultured in the absence of DMSO and this effect appeared to be reversible upon removal of the PCMS. © 1979.

引用

页码：1148 / 1156

页数：9

共 16 条

[1] A MODIFICATION OF THE BENZIDINE METHOD FOR MEASUREMENT OF HEMOGLOBIN IN PLASMA AND URINE [J].