SYNTHESIS OF 6-HYDROXIMINO-3-OXO STEROIDS, A NEW CLASS OF AROMATASE INHIBITOR

被引：40

作者：

HOLLAND, HL ^{[1
]}

KUMARESAN, S ^{[1
]}

TAN, L ^{[1
]}

NJAR, VCO ^{[1
]}

机构：

[1] UNIV SHERBROOKE,SCH MED,DEPT BIOCHEM,SHERBROOKE J1H 5N4,QUEBEC,CANADA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 05期

关键词：

D O I：

10.1039/p19920000585

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(E)-3-beta,17-beta-Dihydroxyandrost-4-en-6-one oxime has been converted into (E)-6- hydroximinotestosterone and (E)-6-hydroximinoandrost-4-ene-3,17-dione by chemical methods, and into (E)-6-hydroximinoandrosta-1,4-diene-3,17-dione by biotransformation using Arthrobacter simplex ATCC 6946.

引用

页码：585 / 587

页数：3

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