ISOLATION AND CHARACTERIZATION OF 2 HUMAN H1 HISTONE GENES WITHIN CLUSTERS OF CORE HISTONE GENES

被引:79
作者
ALBIG, W [1 ]
KARDALINOU, E [1 ]
DRABENT, B [1 ]
ZIMMER, A [1 ]
DOENECKE, D [1 ]
机构
[1] MAX PLANCK INST EXPTL MED,MOLEK NEUROENDOKRINOL ABT,W-3400 GOTTINGEN,GERMANY
关键词
D O I
10.1016/0888-7543(91)90183-F
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Two human H1 histone genes, termed H1.3 and H1.4, were isolated from two cosmid clones. The H1.4 gene is associated with an H2B gene, whereas genes coding for all four core histones are located in the vicinity of the H1.3 gene. This cluster arrangement was found both in the two cosmid clones and on overlapping bacteriophage clones isolated from an EMBL3 library. In continuation of our previous analysis of two human H1 genes, this analysis raises the number of completely sequenced H1 histone genes within clusters of core histone genes to four. © 1991.
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页码:940 / 948
页数:9
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