Eculizumab application during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: A case report with review of the literature

被引：4
作者：
Lauritsch-Hernandez, Lisa Sophie [1 ]
Kraehenmann, Franziska [1 ]
Balabanov, Stefan [2 ]
Kimmich, Nina [1 ]
机构：
[1] Univ Hosp Zurich, Dept Obstet, Zurich, Switzerland
[2] Univ Hosp Zurich, Dept Hematol, Zurich, Switzerland
来源：
CLINICAL CASE REPORTS | 2018年 / 6卷 / 08期
关键词：
eculizumab; management; maternal and fetal outcome; paroxysmal nocturnal hemoglobinuria; pregnancy;
D O I：
10.1002/ccr3.1634
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Key Clinical Message Eculizumab is highly effective in inhibiting complement activation and has successfully shown to prevent complications and to improve quality of life in patients with paroxysmal nocturnal hemoglobinuria (PNH). Its application during pregnancy showed favorable fetal and maternal outcome in the presented case and has proven to be effective without raising safety concerns.
引用
收藏
页码：1582 / 1587
页数：6
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