Acute generalized exanthematous pustulosis induced by amoxicillin-clavulanate

被引:0
作者
Nacaroglu, Hikmet Tekin [1 ]
Bent, Sultan [2 ]
Ceylan, Yasemin [2 ]
Bostantan Gayayret, Ozlem [2 ]
Erol, Meltem [2 ]
机构
[1] Bagcilar Egitim & Arastirma Hastanesi, Cocuk Allerji, Istanbul, Turkey
[2] Bagcilar Egitim & Arastirma Hastanesi, Cocuk Klin, Istanbul, Turkey
来源
Izmir Dr Behcet Uz Cocuk Hastanesi Dergisi | 2016年 / 6卷 / 03期
关键词
Acute generalized exanthematous pustulosis; amoxicillin-clavulanate; children; drug hypersensitivity;
D O I
10.5222/buchd.2016.215
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous rash characterized by the abrupt onset of a widespread generalized pustular rash all over the body often accompanied by fever. In the etiopathogenesis, there is a history of drug use in 90% of the cases, and occasionally hypersensitivity reactions to mercury or viral and bacterial infections are accused. Herein, a patient under amoxicillin-clavulanate therapy is presented who was diagnosed clinically as AGEP according to the scoring system by EuroSCAR group. As these reactions are known to emerge rarely emerge depending upon frequently used drugs, we have intended to draw attention to infections seen in childhood in the etiology of the rashes and drug reactions as well.
引用
收藏
页码:215 / 218
页数:4
相关论文
共 13 条
[1]   Mercury-induced acute generalized exanthematous pustulosis misdiagnosed as a drug-related case [J].
Belhadjali, Hichem ;
Mandhouj, Selsabil ;
Moussa, Adnene ;
Njim, Leila ;
Amri, Montassar ;
Zakhama, Abdelfattah ;
Zili, Jameleddine .
CONTACT DERMATITIS, 2008, 59 (01) :52-U23
[2]   Acute generalized exanthematous pustulosis [J].
Beylot, C ;
Doutre, MS ;
BeylotBarry, M .
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 1996, 15 (04) :244-249
[3]  
BEYLOT C, 1980, ANN DERMATOL VENER, V107, P37
[4]   Acute generalized exanthematous pustulosis (AGEP) induced by cefotaxime [J].
Chaabane, Amel ;
Aouam, Karim ;
Gassab, Lies ;
Njim, Leila ;
Boughattas, Naceur A. .
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2010, 24 (04) :429-432
[5]  
Freedberg IM, 2003, FITZPATRICKS DERMATO, P625
[6]   The spectrum of histopathological features in acute generalized exanthematous pustulosis: a study of 102 cases [J].
Halevy, S. ;
Kardaun, S. H. ;
Davidovici, B. ;
Wechsler, J. .
BRITISH JOURNAL OF DERMATOLOGY, 2010, 163 (06) :1245-1252
[7]   Acute generalized exanthematous pustulosis induced by ceftriaxone use [J].
Nacaroglu, Hikmet Tekin ;
Celegen, Mehmet ;
Ozek, Gulcihan ;
Umac, Ozgur ;
Karkiner, Canan Sule Unsal ;
Yildirim, Hulya Tosun ;
Can, Demet .
POSTEPY DERMATOLOGII I ALERGOLOGII, 2014, 31 (04) :269-271
[8]   Is acute generalized exanthematous pustulosis an uncommon condition in childhood? [J].
Ozmen, S. ;
Misirlioglu, E. D. ;
Gurkan, A. ;
Arda, N. ;
Bostanci, I. .
ALLERGY, 2010, 65 (11) :1490-1492
[9]   ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS - ANALYSIS OF 63 CASES [J].
ROUJEAU, JC ;
BIOULACSAGE, P ;
BOURSEAU, C ;
GUILLAUME, JC ;
BERNARD, P ;
LOK, C ;
PLANTIN, P ;
CLAUDY, A ;
DELAVIERRE, C ;
VAILLANT, L ;
WECHSLER, J ;
DANAN, G ;
BENICHOU, C ;
BEYLOT, C .
ARCHIVES OF DERMATOLOGY, 1991, 127 (09) :1333-1338
[10]   Risk factors for acute generalized exanthematous pustulosis (AGEP) - results of a multinational case-control study (EuroSCAR) [J].
Sidoroff, A. ;
Dunant, A. ;
Viboud, C. ;
Halevy, S. ;
Bavinck, J. N. Bouwes ;
Naldi, L. ;
Mockenhaupt, M. ;
Fagot, J-P. ;
Roujeau, J-C. .
BRITISH JOURNAL OF DERMATOLOGY, 2007, 157 (05) :989-996