Consider Behcet's disease in young patients with deep vein thrombosis

被引:8
作者
Gungen, Adil Can [1 ]
Coban, Hikmet [1 ]
Aydemir, Yusuf [1 ]
Duzenli, Hasan [1 ]
机构
[1] Sakarya Univ, Res & Training Hosp, Dept Pulmonol, TR-54100 Sakarya, Turkey
关键词
Behcet's disease; Deep vein thrombosis; Pulmonary embolism; Immunosuppressant therapy;
D O I
10.1016/j.rmcr.2016.04.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Behcet's disease is a multi-systemic and chronic inflammatory vasculitis of unknown etiology characterized by recurrent oral and genital ulcers, uveitis, arthritis, arterial aneurysms, venous thrombosis, skin lesions and GIS lesions. Although pulmonary artery aneurysms are rare, it is a critical condition due to high risk of rupture. Venous involvement of Behcet's disease primarily occurs in the lower extremities. In the presence of deep vein thrombosis(DVT) and pulmonary embolism, the mainstay of treatment in Behcet's disease is immunosuppressant therapy. Anticoagulants can be used only after initiation of immunosuppressant therapy and suppression of the disease. Anticoagulant therapy alone may lead to fatal hemoptysis. We report the case of a 24 year-old patient who presented to the emergency service with complaints of shortness of breath, general condition disorder and hemoptyhis while using warfarin for DVT and whose thoracic CT angiography showed pulmonary embolism and pulmonary artery aneurysm and diagnosed with Behcet's disease. (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
引用
收藏
页码:41 / 44
页数:4
相关论文
共 15 条
[1]   Treatment of venous thrombosis associated with Behcet's disease: immunosuppressive therapy alone versus immunosuppressive therapy plus anticoagulation [J].
Ahn, Joong Kyong ;
Lee, You Sun ;
Jeon, Chan Hong ;
Koh, Eun-Mi ;
Cha, Hoon-Suk .
CLINICAL RHEUMATOLOGY, 2008, 27 (02) :201-205
[2]  
BAYRAKTAR Y, 1995, AM J GASTROENTEROL, V90, P1476
[3]  
Cakmak OS, 2010, CLIN EXP RHEUMATOL, V28, pS139
[4]   Pulmonary manifestations of Behcet's disease [J].
Erkan, F ;
Gül, A ;
Tasali, E .
THORAX, 2001, 56 (07) :572-578
[5]  
Filali-Ansary N, 1999, ANN MED INTERNE, V150, P657
[6]   Pulmonary artery aneurysms in Behcet syndrome [J].
Hamuryudan, V ;
Er, T ;
Seyahi, E ;
Akman, C ;
Tüzün, H ;
Fresko, I ;
Yurdakul, S ;
Numan, R ;
Yazici, H .
AMERICAN JOURNAL OF MEDICINE, 2004, 117 (11) :867-870
[7]   Other forms of vasculitis and pseudovasculitis [J].
Hamuryudan, V ;
Ozdogan, H ;
Yazici, H .
BAILLIERES CLINICAL RHEUMATOLOGY, 1997, 11 (02) :335-355
[8]  
HAMURYUDAN V, 1994, BRIT J RHEUMATOL, V33, P48
[9]   Is anticoagulation unnecessary in Behcet's disease with deep venous thrombosis? [J].
Korkmaz, Cengiz .
CLINICAL RHEUMATOLOGY, 2008, 27 (03) :405-406
[10]  
Masuda K, 1975, JPN J OPHTHALMOL, V19, P278