THE PRODUCTION POTENTIAL OF EICOSAPENTAENOIC AND ARACHIDONIC ACIDS BY THE RED ALGA PORPHYRIDIUM-CRUENTUM
被引:66
作者:
COHEN, Z
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机构:The Laboratory for Microalgal Biotechnology, Jacob Blaustein Institute for Desert Research, Ben-Gurion University of the Negev, 84993, Sede-Boker Campus
COHEN, Z
机构:
[1] The Laboratory for Microalgal Biotechnology, Jacob Blaustein Institute for Desert Research, Ben-Gurion University of the Negev, 84993, Sede-Boker Campus
The red microalga Porphyridium cruentum is a new source for eicosapentanoic acid (EPA) and arachidonic acid (AA) fatty acids of potential pharmaceutical value. The conditions leading to a high content of either fatty acid were investigated. The highest EPA content was obtained under conditions resulting in high growth rate (2.4% of ash free dry weight in Strain 1380-1d). High AA content was obtained under slow growth conditions and was maximal in the stationary phase or under nitrogen starvation (2.9%). Strain 1380-1a had the highest content (1.9%) of arachidonic acid under exponential growth conditions. By imposing nitrogen starvation, it was possible to obtain a lipid mixture which may be separated into AA and EPA rich fractions.