CARDIOVASCULAR EFFECTS OF PAROXETINE

被引：37
作者：
KUHS, H
RUDOLF, GAE
机构：
[1] Department of Psychiatry, University of Münster, Münster, D-4400
来源：
PSYCHOPHARMACOLOGY | 1990年 / 102卷 / 03期
关键词：
Amitriptyline; Blood pressure; Electrocardiogram; Paroxetine; Plasma drug concentration; Systolic time intervals;
D O I：
10.1007/BF02244107
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured. © 1990 Springer-Verlag.
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页码：379 / 382
页数：4
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