SINGLE STRANDS INDUCE RECA PROTEIN TO UNWIND DUPLEX DNA FOR HOMOLOGOUS PAIRING

被引：147

作者：

CUNNINGHAM, RP ^{[1
]}

SHIBATA, T ^{[1
]}

DASGUPTA, C ^{[1
]}

RADDING, CM ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT MOLEC BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510

来源：

NATURE | 1979年 / 281卷 / 5728期

关键词：

D O I：

10.1038/281191a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Single-stranded DNA, whether homologous or not, stimulates purified Escherichia coli recA protein to unwind duplex DNA. This helps to explain how recA promotes a search for homology in genetic recombination. As oligodeoxynucleotides also stimulate unwinding, a common mechanism may relate the function of recA protein in recombination to other functions (SOS) induced by oligonucleotides. © 1979 Nature Publishing Group.

引用

页码：191 / 195

页数：5

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