SINGLE STRANDS INDUCE RECA PROTEIN TO UNWIND DUPLEX DNA FOR HOMOLOGOUS PAIRING

被引：147
作者：
CUNNINGHAM, RP [1 ]
SHIBATA, T [1 ]
DASGUPTA, C [1 ]
RADDING, CM [1 ]
机构：
[1] YALE UNIV,SCH MED,DEPT MOLEC BIOPHYS & BIOCHEM,NEW HAVEN,CT 06510
来源：
NATURE | 1979年 / 281卷 / 5728期
关键词：
D O I：
10.1038/281191a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Single-stranded DNA, whether homologous or not, stimulates purified Escherichia coli recA protein to unwind duplex DNA. This helps to explain how recA promotes a search for homology in genetic recombination. As oligodeoxynucleotides also stimulate unwinding, a common mechanism may relate the function of recA protein in recombination to other functions (SOS) induced by oligonucleotides. © 1979 Nature Publishing Group.
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页码：191 / 195
页数：5
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