USE OF POROUS BIODEGRADABLE POLYMER IMPLANTS IN MENISCUS RECONSTRUCTION .2. BIOLOGICAL EVALUATION OF POROUS BIODEGRADABLE POLYMER IMPLANTS IN MENISCI

被引：43

作者：

ELEMA, H

DEGROOT, JH

NIJENHUIS, AJ

PENNINGS, AJ

VETH, RPH

KLOMPMAKER, J

JANSEN, HWB

机构：

[1] STATE UNIV GRONINGEN,DEPT POLYMER CHEM,NIJENBORGH 16,9747 AG GRONINGEN,NETHERLANDS

[2] STATE UNIV GRONINGEN HOSP,DEPT ORTHOPAED SURG,9700 RB GRONINGEN,NETHERLANDS

[3] STATE UNIV GRONINGEN HOSP,DEPT SURG,9700 RB GRONINGEN,NETHERLANDS

[4] STATE UNIV GRONINGEN HOSP,DEPT HISTOL & CELL BIOL,9700 RB GRONINGEN,NETHERLANDS

来源：

COLLOID AND POLYMER SCIENCE | 1990年 / 268卷 / 12期

关键词：

POROUS MATERIALS; BIODEGRADABLE FOAMS; MENISCUS RECONSTRUCTION; MACROPORE SIZE; INTERCONNECTED PORES; PORE VOLUME;

D O I：

10.1007/BF01410673

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Several series of porous, biodegradable PU/PLLA foams were used for meniscus reconstruction in dogs. PLLA-fiber reinforced PU/PLLA composites, PU/PLLA, and PU foams were implanted in severe meniscus lesions. The healing process was initiated as a result of blood vessels' and other cells' ingrowth into these porous materials. To accomplish good ingrowth of fibrocartilaginous tissue, the materials should have interconnected macropores of 200-300-mu-m with a high total pore volume. PLLA fibers were used to reinforce the materials, but seem to retard the degradation process and the ingrowth of fibrocartilaginous tissue.

引用

页码：1082 / 1088

页数：7

共 30 条

[1] WINNER OF THE 1982 ODONOGHUE AWARD - THE MICROVASCULATURE OF THE MENISCUS AND ITS RESPONSE TO INJURY - AN EXPERIMENTAL-STUDY IN THE DOG [J].