MATHEMATICAL-MODEL FOR STUDYING GENETIC-VARIATION IN TERMS OF RESTRICTION ENDONUCLEASES

被引：8400
作者：
NEI, M
LI, WH
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 10期
关键词：
D O I：
10.1073/pnas.76.10.5269
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this model are presented for estimating the number of nucleotide substitutions between two populations or species. To express the degree of polymorphism in a population at the nucleotide level, a measure called 'nucleotide diversity' is proposed.
引用
收藏
页码：5269 / 5273
页数：5
相关论文
共 17 条
[1]  
[Anonymous], 1971, STUD GENET
[2]  
AVISE JC, 1979, GENETICS, V92, P279
[3]   RAPID EVOLUTION OF ANIMAL MITOCHONDRIAL-DNA [J].
BROWN, WM ;
GEORGE, M ;
WILSON, AC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (04) :1967-1971
[4]  
BROWN WM, 1976, THESIS CALIFORNIA I
[5]   EVOLUTION OF MITOCHONDRIAL-DNA SEQUENCES IN XENOPUS [J].
DAWID, IB .
DEVELOPMENTAL BIOLOGY, 1972, 29 (02) :139-&
[6]  
KIMURA M, 1969, GENETICS, V61, P893
[7]  
LANGLEY CH, NATURE LONDON
[8]   DIVERSITY OF MITOCHONDRIAL GENOMES AMONG NORMAL CYTOPLASMS OF MAIZE [J].
LEVINGS, CS ;
PRING, DR .
JOURNAL OF HEREDITY, 1977, 68 (06) :350-354
[9]  
LI WH, 1977, GENETICS, V85, P331
[10]  
NEI M, 1980, 14 P INT C GEN MOSC
12