MOLECULAR-BIOLOGY OF HUMAN SALIVARY CYSTEINE PROTEINASE-INHIBITORS

被引：20
|
作者：
SAITOH, E
ISEMURA, S
机构：
来源：
CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE | 1993年 / 4卷 / 3-4期
关键词：
SALIVA; CYSTATIN; PROTEINASE INHIBITOR; AMINO ACID SEQUENCE; CLONING; GENE STRUCTURE; GENE EXPRESSION; MOLECULAR EVOLUTION;
D O I：
10.1177/10454411930040033301
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The synthesis of human cystatins of family II is controlled by a multigene family having at least 7 members that are localized on chromosome 20, the cystatin gene family. Proteolytic degradation and phosphorylation of the gene products give rise to heterogeneity and multiplicity of cystatins in human saliva. These cysteine proteinase inhibitors, as well as other members of the cystatin superfamily, are evolutionally and functionally related to Bowman-Birk type serine proteinase inhibitors.
引用
收藏
页码：487 / 493
页数：7
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