RELATIONSHIP BETWEEN COCHLEAR BLOOD-FLOW AND PERILYMPHATIC OXYGEN-TENSION

被引：6
作者：
KAWAKAMI, M
MAKIMOTO, K
NOI, O
TAKAHASHI, H
机构：
[1] Department of Otolaryngology, Osaka Medical College, Takatsuki, Osaka, 569, 2-7, Daigakucho
来源：
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 1991年 / 248卷 / 08期
关键词：
INNER EAR BLOOD FLOW; OXYGEN TENSION OF PERILYMPH; LASER DOPPLER FLOWMETRY; POLAROGRAPHY; LASER DOPPLER; INCREASES;
D O I：
10.1007/BF00627635
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
To clarify the characteristics of the blood circulation in the cochlea, we correlated cochlear blood flow and perilymphatic oxygen tension at various blood pressures. Cochlear blood flow was measured in guinea pigs by laser Doppler flowmetry, and perilymphatic oxygen tension by polarography. Blood pressure changes were induced by angiotensin II injection, trimetaphan camsylate injection and blood withdrawal. Cochlear blood flow generally paralleled systemic blood pressure, indicating a close correlation. In contrast, perilymphatic oxygen tension was slower to increase and decrease. However, when systemic blood pressure was lowered more gradually, perilymphatic oxygen tension did not show the same lag. These findings indicate that perilymphatic oxygen tension parallels systemic blood pressure when changes induced are slower and in a physiological range.
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页码：465 / 470
页数：6
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