PHENYLETHYLAMINE IN PARANOID CHRONIC-SCHIZOPHRENIA

被引：157
作者：
POTKIN, SG
KAROUM, F
CHUANG, LW
CANNONSPOOR, HE
PHILLIPS, I
WYATT, RJ
机构：
[1] Laboratory of Clinical Psychopharmacology, National Institute of Mental Health, Saint Elizabeths Hospital, Washington
来源：
SCIENCE | 1979年 / 206卷 / 4417期
关键词：
D O I：
10.1126/science.504988
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Phenylethylamine (PEA) is an endogenous amine that is structurally and pharmacologically related to amphetamine. Urinary PEA excretion is significantly higher in paranoid chronic schizophrenics than in nonparanoid chronic schizophrenics and normal controls. Diet, hospitalization, and medication do not account for differences in PEA concentrations. These findings offer some indication that PEA may be an endogenous amphetamine. Copyright © 1979 AAAS.
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页码：470 / 471
页数：2
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