NOVEL DYNAMIC FLOW CYTOENZYMOLOGICAL DETERMINATION OF INTRACELLULAR ESTERASE INHIBITION BY BCNU AND RELATED ISOCYANATES

被引：16

作者：

DIVE, C ^{[1
]}

WORKMAN, P ^{[1
]}

WATSON, JV ^{[1
]}

机构：

[1] MED SCH,MRC,CLIN ONCOL UNIT,HILLS RD,CAMBRIDGE CB2 2QH,ENGLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1987年 / 36卷 / 21期

关键词：

D O I：

10.1016/0006-2952(87)90027-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3731 / 3738

页数：8

共 25 条

[1] ACTIVE-SITE SPECIFIC INACTIVATION OF CHYMOTRYPSIN BY CYCLOHEXYL ISOCYANATE FORMED DURING DEGRADATION OF CARCINOSTATIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA [J].

BABSON, JR ;

REED, DJ ;

SINKEY, MA .

BIOCHEMISTRY, 1977, 16 (08) :1584-1589

[2] INACTIVATION OF GLUTATHIONE REDUCTASE BY 2-CHLOROETHYL NITROSOUREA-DERIVED ISOCYANATES [J].

BABSON, JR ;

REED, DJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 83 (02) :754-762

[3]

BARIL BB, 1975, CANCER RES, V35, P1

[4] ALKYL ISOCYANATES AS ACTIVE-SITE-SPECIFIC REAGENTS FOR SERINE PROTEASES - IDENTIFICATION OF ACTIVE-SITE SERINE AS SITE OF REACTION [J].

BROWN, WE ;

WOLD, F .

BIOCHEMISTRY, 1973, 12 (05) :835-840

[5] MEASUREMENT OF CARBAMOYLATING ACTIVITY OF NITROSOUREAS AND ISOCYANATES BY A NOVEL HIGH-PRESSURE LIQUID-CHROMATOGRAPHY ASSAY [J].

BRUBAKER, WF ;

ZHAO, HP ;

PRUSOFF, WH .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (14) :2359-2365

[6]

COLVIN M, 1981, NITROSOUREAS, P43

[7]

DIVE C, IN PRESS CYTOMETRY

[8]

GROSS M, 1975, J BIOL CHEM, V250, P7693

[9] LIPOLYSIS OF FLUORESCEIN AND EOSIN ESTERS . KINETICS OF HYDROLYSIS [J].

GUILBAULT, GG ;

KRAMER, DN .

ANALYTICAL BIOCHEMISTRY, 1966, 14 (01) :28-+

[10]

JOHNSTON TP, 1986, CANCER TREAT REP, V70, P13

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