ONLINE COUPLING OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND NUCLEAR MAGNETIC-RESONANCE

被引：94

作者：

BAYER, E ^{[1
]}

ALBERT, K ^{[1
]}

NIEDER, M ^{[1
]}

GROM, E ^{[1
]}

机构：

[1] BRUKER ANALYT MESSTECH GMBH,D-7512 RHEINSTETTEN FO,FED REP GER

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 186卷 / DEC期

关键词：

D O I：

10.1016/S0021-9673(00)95270-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

High-performance liquid chromatography-nuclear magnetic resonance (HPLC-NMR) on-line coupling is a possible solution to the problemof universal detectors in liquid chromatogrphy. By use of a newly developed 1H-FT-NMR* flow cell, 1H-NMR spectra of flowing systems cn be obtained. Although sensitivity and resolution are somewhat lower than in the conventional system, the 1H-MNMR spectra are of sufficient quality to enable classification of unknown compounds. The performed HPLC separation with on-line NMR-measurement shows the capabilities of the applied arrangement. © 1979.

引用

页码：497 / 507

页数：11

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