PREPARATIVE SCALE SEPARATION OF XANTHONES AND IRIDOID GLYCOSIDES BY DROPLET COUNTERCURRENT CHROMATOGRAPHY

被引：24
作者：
HOSTETTMANN, K
HOSTETTMANNKALDAS, M
STICHER, O
机构：
[1] Pharmazeutisches Institut, Eidgenössische Technische Hochschule, ETH-Zentrum, Zürich
来源：
HELVETICA CHIMICA ACTA | 1979年 / 62卷 / 07期
关键词：
D O I：
10.1002/hlca.19790620705
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Droplet counter‐current chromatography (DCCC.) has been used for the preparative scale separation of pure constituents from crude medicinal plant extracts. Xanthones and the bitter principles have been isolated from North‐American Gentiana species. From a crude extract of Ajuga pyramidalis L. Labiatae, several hundred mg of iridoid glycosides were obtained within eight hours. The total volume of mobile phase employed for the elution was less than 150 ml. All the separations were achieved far more readily than by conventional chromatography. In addition, some general rules for solvent system selection are proposed. Copyright © 1979 Verlag GmbH & Co. KGaA, Weinheim
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页码：2079 / 2085
页数：7
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