Advances in Oncology Care Targeted Therapies

被引:5
作者
Beatty, Kristi [1 ]
Winkelman, Christine [2 ]
Bokar, Joseph A. [1 ]
Mazanec, Polly [2 ]
机构
[1] Univ Hosp, Seidman Canc Ctr, Wearn 552,11100 Euclid Ave, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA
关键词
biology; cancer; chemotherapy; oncology; radiation; targeted therapy;
D O I
10.1097/NCI.0b013e3182310178
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
The start of the 21st century has produced advances in cancer care that have improved both survival rates and quality of life for many persons diagnosed with cancer. Targeted therapy has given new hope for controlling cancer as a chronic illness. Alone, or in combination with traditional therapies such as surgery, radiation, and/or chemotherapy, this new form of therapy targets malignant cells, halting tumor growth and the potential metastatic spread of disease. Toxicities are limited, but some are serious and may require intensive care. It is imperative for the experienced critical care nurse to have an understanding of these new treatment options and those on the horizon, as these therapies are the future of cancer care. Whereas in previous decades, patients with cancer may not have survived an intensive care admission for treatment complications or advanced disease, many patients now are recovering from life-threatening events, continuing treatment for their disease, and going on to live meaningful, good-quality lives.
引用
收藏
页码:323 / 334
页数:12
相关论文
共 26 条
[11]   Special nursing considerations [J].
Kaplow, R .
CRITICAL CARE CLINICS, 2001, 17 (03) :769-+
[12]   Intensive care unit outcomes in elderly cancer patients [J].
Karamlou, K ;
Nichols, DJ ;
Nichols, CR .
CRITICAL CARE CLINICS, 2003, 19 (04) :657-+
[13]  
Kurtin SE, 2007, CANC NURS, V30, P51
[14]   Outcome analysis of 189 consecutive cancer patients referred to the intensive care unit as emergencies during a 2-year period [J].
Maschmeyer, G ;
Bertschat, FL ;
Moesta, KT ;
Häusler, E ;
Held, TK ;
Nolte, M ;
Osterziel, KJ ;
Papstein, V ;
Peters, M ;
Reich, G ;
Schmutzler, M ;
Sezer, O ;
Stula, M ;
Wauer, H ;
Wörtz, T ;
Wischnewsky, M ;
Hohenberger, P .
EUROPEAN JOURNAL OF CANCER, 2003, 39 (06) :783-792
[15]   ICU and 6-month outcome of oncology patients in the intensive care unit [J].
McGrath, S. ;
Chatterjee, F. ;
Whiteley, C. ;
Ostermann, M. .
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2010, 103 (06) :397-403
[16]  
Mukherjee Siddhartha, 2010, EMPEROR ALL MALADIES
[17]   Cardiac toxicity of ErbB2-targeted therapies: What do we know? [J].
Perez, Edith A. .
CLINICAL BREAST CANCER, 2008, 8 :S114-S120
[18]  
Rote N. S., 2010, PATHOPHYSIOLOGY BIOL
[19]   Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor-Targeted Therapy in Metastatic Colorectal Cancer [J].
Siena, Salvatore ;
Sartore-Bianchi, Andrea ;
Di Nicolantonio, Federica ;
Balfour, Julia ;
Bardelli, Alberto .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2009, 101 (19) :1308-1324
[20]   Survival and predictors of outcome in patients with acute leukemia admitted to the intensive care unit [J].
Thakkar, Snehal G. ;
Fu, Alex Z. ;
Sweetenham, John W. ;
Mciver, Zachariah A. ;
Mohan, Sanjay R. ;
Ramsingh, Giridharan ;
Advani, Anjali S. ;
Sobecks, Ronald ;
Rybicki, Lisa ;
Kalaycio, Maff ;
Sekeres, Mikkael A. .
CANCER, 2008, 112 (10) :2233-2240