EFFECT OF HERPES SIMPLEX VIRUS ON HUMAN EMBRYONIC CELLS LATENTLY INFECTED WITH REOVIRUS TYPE 3

被引：3

作者：

BELL, TM

MUNUBE, GMR

GRIFFIN, ER

机构：

[1] Imperial Cancer Research Fund, Entebbe

[2] Wellcome Electron Microscope Unit, Makerere University College Medical School, Kampala

来源：

INTERNATIONAL JOURNAL OF CANCER | 1968年 / 3卷 / 06期

关键词：

D O I：

10.1002/ijc.2910030608

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A persistent latent infection of human embryo fibroblasts by reovirus type 3 was found to be due to the continuous infection of a small proportion of the cells. Super‐infection of these cultures by herpes simplex virus resulted in the destruction of the monolayers by the herpes virus without any obvious signs of interference. Electron microscopic examination of these doubly infected cultures showed the presence of multi‐nuclear blebs and an unusual, “condensed‐mass”, form of intranuclear herpes virus. The implications of these findings are discussed. Copyright © 1968 Wiley‐Liss, Inc., A Wiley Company

引用

页码：751 / &

共 26 条

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