SYNTHESIS OF N-GLYCOSYLATED PYRIDINES AS NEW ANTIVIRAL AGENTS

被引:23
|
作者
IBRAHIM, ES
ELGEMEIE, GEH
ABBASI, MM
ABBAS, YA
ELBADAWI, MA
ATTIA, AME
机构
[1] SUEZ CANAL UNIV,FAC SCI,DEPT CHEM,SUEZ,EGYPT
[2] CAIRO UNIV,FAC SCI,DEPT CHEM,BANI SUEF BRANCH,CAIRO,EGYPT
[3] TANTA UNIV,FAC SCI,DEPT CHEM,TANTA,EGYPT
[4] TANTA UNIV,FAC EDUC,DEPT CHEM,TANTA,EGYPT
来源
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 06期
关键词
D O I
10.1080/15257779508010701
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A series of 3-cyanopyridine glycosides have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) replication in MT-4 cells. Among the 3-cyanopyridine glycosides 6-(p-methylphenyl) and 6-(p-aminophenyl) were the most selective inhibitors of HIV replication.
引用
收藏
页码:1415 / 1423
页数:9
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