ENANTIOMERIC SEPARATION BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CHROMATOGRAPHY USING BILE-SALT

被引：33
作者：
LIN, M
WU, NA
BARKER, GE
SUN, P
HUIE, CW
HARTWICK, RA
机构：
[1] Department of Chemistrv, State University of New York at Binghamton, Binghamton, New York
来源：
JOURNAL OF LIQUID CHROMATOGRAPHY | 1993年 / 16卷 / 17期
关键词：
D O I：
10.1080/10826079308019659
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A method for enantiomeric separation by cyclodextrin-modified micellar electrokinetic chromatography (MEKC) with bile salt micelles is described. The enantiomeric resolution was achieved with a mixed sodium taurodeoxycholate (TDC)-beta-cyclodextrin (CD) solution (pH 7-9) utilizing a bare capillary. In sodium dodecyl sulfate (SDS)-CD solutions, similar result were not obtained. The effect of varying concentrations of TCD and beta-CD and pH on the selectivity and resolution were also briefly investigated.
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收藏
页码：3667 / 3674
页数：8
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