COMPARATIVE STUDY OF SERUM LDH, URIC ACID AND ALKALINE PHOSPHATASE IN PREECLAMPSIA VERSUS NORMOTENSIVE PREGNANT WOMAN

BACKGROUND Our aim is to compare the serum levels of Lactate Dehydrogenase (LDH), alkaline phosphatase and uric acid in preeclampsia versus normotensive pregnant woman and correlate their levels with the severity of the disease. MATERIALS AND METHODS 100 antenatal patients having preeclampsia and equal no. of normotensive patients were chosen. About 3 mL of blood was drawn under aseptic precautions from selected subjects in a plain vial for serum. Serum was separated by centrifugation and used for estimation of serum levels of LDH alkaline phosphatase and UA. RESULTS We have observed significant difference in serum LDH, alkaline phosphatase and uric acid in hypertensive group patients in comparison with normotensive patients. CONCLUSION We conclude that serum LDH, ALP, Serum Uric Acid are reliable and inexpensive markers to predict severity and maternal and foetal outcome in preeclampsia.