A GENERAL-SYNTHESIS OF N-SUBSTITUTED ISOTHIAZOL-3(2H)-ONES

被引：13

作者：

BEELEY, NRA

HARWOOD, LM

HEDGER, PC

机构：

[1] UNIV OXFORD,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

[2] CELLTECH LTD,SLOUGH SL1 4EN,BERKS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 16期

关键词：

D O I：

10.1039/p19940002245

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general route to the synthesis of N-substituted isothiazol-3(2H)-ones (4a-i) is described which proceeds via trichloroacetic acid-mediated ring closure of N-substituted (Z)-3-(benzylsulfinyl) propenamides (15a-i).

引用

页码：2245 / 2251

页数：7

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