HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM AND 4 OF ITS METABOLITES IN PLASMA - EVALUATION OF THEIR STABILITY

被引：36

作者：

DUBE, LM ^{[1
]}

MOUSSEAU, N ^{[1
]}

MCGILVERAY, IJ ^{[1
]}

机构：

[1] HLTH PROTECT BRANCH,BUR DRUG RES,DIV PHARMACEUT CHEM,BANTING RES CTR,TUNNEYS PASTURE,OTTAWA K1A 0L2,ONTARIO,CANADA

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1988年 / 430卷 / 01期

关键词：

D O I：

10.1016/S0378-4347(00)83138-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：103 / 111

页数：9

共 16 条

[1] DILTIAZEM AND DESACETYLDILTIAZEM ANALYSIS IN HUMAN-PLASMA USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - IMPROVED SENSITIVITY WITHOUT DERIVATIZATION [J].

ABERNETHY, DR ;

SCHWARTZ, JB ;

TODD, EL .

JOURNAL OF CHROMATOGRAPHY, 1985, 342 (01) :216-220

[2] SURFACE SILANOLS IN SILICA-BONDED HYDROCARBONACEOUS STATIONARY PHASES .2. IRREGULAR RETENTION BEHAVIOR AND EFFECT OF SILANOL MASKING [J].

BIJ, KE ;

HORVATH, C ;

MELANDER, WR ;

NAHUM, A .

JOURNAL OF CHROMATOGRAPHY, 1981, 203 (JAN) :65-84

[3]

CAILLE G, 1988, IN PRESS BIOPHARM DR, V9

[4] DILTIAZEM - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC EFFICACY [J].

CHAFFMAN, M ;

BROGDEN, RN .

DRUGS, 1985, 29 (05) :387-454

[5] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM AND 6 OF ITS METABOLITES IN HUMAN-URINE [J].

CLOZEL, JP ;

CAILLE, G ;

TAEYMANS, Y ;

THEROUX, P ;

BIRON, P ;

TRUDEL, F .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1984, 73 (06) :771-773

[6] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM AND 4 OF ITS METABOLITES IN PLASMA - APPLICATION TO PHARMACOKINETICS [J].

GOEBEL, KJ ;

KOLLE, EU .

JOURNAL OF CHROMATOGRAPHY, 1985, 345 (02) :355-363

[7] LIQUID-CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM AND ITS METABOLITES USING TRANS ISOMERS AS INTERNAL STANDARDS, WITH DYNAMIC MODIFICATION OF THE SOLID-PHASE BY ADDITION OF AN AMINE TO THE MOBILE PHASE [J].

HOGLUND, P ;

NILSSON, LG .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1987, 414 (01) :109-120

[8]

JOHNSON SM, 1987, J LIQ CHROMATOGR, V10, P673

[9]

KIEL JS, 1985, J CHROMATOGR, V320, P313

[10] A RAPID HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS MEASUREMENT OF 6 TRICYCLIC ANTIDEPRESSANTS [J].

KIEL, JS ;

ABRAMSON, RK ;

MORGAN, SL ;

VORIS, JC .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1983, 6 (14) :2761-2773

← 1 2 →