WORSENING OF VASOVAGAL SYNCOPE AFTER BETA-BLOCKER THERAPY

被引：8

作者：

WANG, CC ^{[1
]}

YEH, SJ ^{[1
]}

WEN, MS ^{[1
]}

LIN, FC ^{[1
]}

WU, D ^{[1
]}

机构：

[1] CHANG GUNG MEM HOSP,CHANG GUNG MED COLL,DEPT MED,CARDIOL SECT,TAIPEI,TAIWAN

来源：

CHEST | 1994年 / 106卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1378/chest.106.3.963

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Head-up tilt test was done in a 27-year-old man with recurrent syncope of unexplained cause. Severe sinus bradycardia and hypotension accompanied by lightheadedness, cold sweating, and nausea occurred at 80 degrees head-up position during 4 mu g/min isoproterenol infusion. Oral propranolol, 160 mg/d, in four divided doses, effectively prevented the above-mentioned abnormal vasovagal reflexes; diltiazem was only partially effective while disopyramide, aminophylline, or atropine was ineffective in preventing the abnormal vasovagal reflexes induced by head-up tilt with isoproterenol infusion. However, the patient experienced ten episodes of syncope in 2 weeks after he was discharged from the hospital on a regimen of atenolol, 50 mg/d. His symptoms ameliorated immediately after discontinuation of atenolol therapy and he became free of severe symptoms while receiving fludrocortisone. Thus, we have documented a patient with worsening of vasovagal syncope after beta-blocker therapy.

引用

页码：963 / 965

页数：3